TREP, the TRansposable Elements Platform

Superfamily Mutator                   DTM

Full classification: DNA-transposon, TIR, Mutator

Mutator elements are Class 2 transposons.

They are widespread in eukaryotes and very abundant in plants. A very useful diagnostic feature is the long TSD. The terminal repeats usually end in GA (5' end) and TC (3' end).
Upon insertion, they create a 9 bp Target site duplication (TSD).

Structure of Mutator elements

Sequence domains

TIR5: Terminal inverted repeat
Function: Contains motifs that are recognized and bound by the transposase. Essential for transposition.
Protein motifs:

TASE: Transposase
Function: Required for excision and insertion
Protein motifs: DDE

TIR3: Terminal inverted repeat
Function: Contains motifs that are recognized and bound by the transposase. Essential for transposition.
Protein motifs:

243 Mutator Download all 'DTM' elements in total_TREP database elements from the following taxa are in the total_TREP database:

Taxonomic group	Total elements
ANIMALIA	3
FUNGI	1
PLANTAE	239

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